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Activating GLP-1R inhibits PFKFB3-driven glycolysis and histone lactylation in TGF-1 + IL-1-stimulated fibroblasts Our results demonstrated that TGF-1 + IL-1 augmented PFKFB3-driven glycolysis, lactate production and histone lactylation in fibroblasts in vitro (Fig

v) The synthesis and preparation process of G/D-CuP are straightforward and cost-effective, making it highly promising for clinical translation

Talebi M, Talebi M, Farkhondeh T, Mishra G, lgn S, Samarghandian S

Disease-specific, versus standard, nutritional support for the treatment of pressure ulcers in institutionalized older adults: a randomized controlled trial