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After discontinuation, close monitoring is essential: weight should be checked every 4-8 weeks initially, and for diabetes patients, self-monitoring of blood glucose or continuous glucose monitoring should continue as indicated, with A1C assessment within approximately 3 months of stopping to detect metabolic deterioration early and implement alternative management strategies

Women must have a negative pregnancy test before starting Qsymia and each month while taking the medication

Microbiota-derived genotoxin tilimycin generates colonic stem cell mutations