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As Comorbidities Rise, GLP-1s Gain Ground Beyond Diabetes and Obesity Among the many conditions that frequently overlap with T2D and obesity, obstructive sleep apnea (OSA), MASHa subset of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), hypertension, and high cholesterol are among the most prevalent

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HUVECs, in particular, act as semi-professional antigen-presenting cells, expressing major histocompatibility complex (MHC) class I constitutively and MHC class II in an inducible manner, thus potentially enhancing T-cell activation and distorting disease modelling (199, 200)