Moreover, insulin resistance of the adipose tissue, associated with overweight/obesity, contributes to the flux of FFA from adipose tissue to the liver through unrestricted lipolysis ( de novo lipogenesis, i.e., hepatic FFA synthesis, seems to contribute to lipid deposition ( Figure 2 The gut-derived incretin hormones GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) are responsible for the so-called incretin effect (i.e., the potentiation of glucose-stimulated insulin secretion after meal ingestion) ( Glucagon is a key hormone in the regulation of overall energy homeostasis during the fasting state and other energy-demanding situations
Huang, B., Wang, W., Bates, M
10.5415/apallergy.2014.4.1.68 Asia Pac
2024;604:217258 Zhou Y, Zou J, Xu J, Zhou Y, Cen X, Zhao Y