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New therapeutic approaches that use drugs to ameliorate the downstream sequelae of HbS polymerization have not proved to be as effective as hydroxyurea (HU) which has an anti-sickling effect via induction of fetal hemoglobin (HbF, 22) (Ware and Aygun, 2009)

But now, doctors often give it off-label for weight reduction and other issues like PCOS

IUPAC name: 1-Methylquinolin-1-ium-5-amine