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Robust clinical evidence supports the inclusion of agents such as semaglutide and liraglutide for reducing HbA1c levels, achieving substantial weight loss, and mitigating complications associated with T2DM and obesity (16)(39)

Persistent severe symptoms warrant clinical review, as 3.9% of participants discontinued therapy due to GI intolerance, especially if fluid loss led to dehydration

The development program of semaglutide 2.4 mg, STEP (Semaglutide Treatment Effect in People with obesity), consistently suggested an even greater BW lowering efficacy compared to SCALE 23

We may get a first glimpse of what savings are like after a newly launched 18-month program that is allowing Medicare to cover GLP-1s for obesity for the first time