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Beta Thalassemia Major is the most severe form the spectrum of Beta Thalassemias with the thalassemia trait or minor being only carriers with only mild anemia or even normal hemoglobin levels and Thalassemia Intermedia patients being less severely anemia than Thalassemia Major and requiring start of transfusions at a later age than children with Thalassemia Major

In clinical studies, participants taking Retatrutide experienced up to 24% weight loss over 48 weeks, more than observed with current GLP-1 treatments