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Recently we reported that the AT4 receptor antagonist Norleual- AngIV (Nle-YI--(CH2-NH2)-HPF) inhibited HGF binding to c-Met and in turn HGF-dependent signaling, proliferation, invasion, and scattering [78]

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DSIP has been described as influencing GABA-A receptor activity in a way sometimes compared to benzodiazepines but, importantly, without the sedation or dependence profile associated with those drugs

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