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While caffeine has been shown to increase sex hormone binding globulin (SHBG), which can slightly lower the levels of free testosterone, these effects are not substantial enough at normal caffeine consumption levels to raise concerns 1

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Funding This work was supported by the National Science and Technology Major Project (2022ZD0117700), the National Natural Science Foundation of China (32270759) and the Research Foundation for Postdoctoral (AUGA5710026124)