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Gastrointestinal side effects are the most commonly reported adverse effects of tirzepatide, with clinical trials showing dose-dependent rates: nausea (20-33%), diarrhea (12-23%), vomiting (9-16%), constipation (11-17%), and abdominal pain

The biggest barrier is the lack of large-scale clinical trials specifically investigating semaglutides effects on OCD

Successful dual kidney transplantation after hypothermic oxygenated perfusion of discarded human kidneys

Definitive answers are eagerly awaited from ongoing trials like the FOCUS study (NCT03811561), which is specifically designed to clarify the long-term impact of semaglutide on diabetic eye disease [96]