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EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2022 update

The arcuate nucleus (ARC) is located near the floor of the third ventricle and the median eminence with a fenestrated epithelium that facilitates hypothalamic sensing of peripheral metabolites and hormones [1, 2] including insulin, serotonin, leptin, and nutrients such as glucose and free fatty acids [35]

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New patients complete an in-person evaluation and baseline labs here