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This is the same receptor activated by natural GHRH, the hypothalamic peptide that controls growth hormone secretion. By mimicking the active region of GHRH, CJC-1295 stimulates the pituitary through the bodys natural GH-release pathway rather than bypassing it with exogenous GH

Li, L., Zeng, Q., Bhutkar, A., Galvan, J., Karamitopoulou, E., Necsulea, A., Noordermeer, D., Piersigilli, A., Peng, M., Perren, A., Ziobec, I., Robinson, H., Iruela-Arispe, M.L., and Hanahan, D., "GKAP acts as a genetic modulator of NMDAR signaling to govern invasive tumor growth", Cancer Cell 33 (4): 736-751 (2018)

The applicant explained that, after propensity score matching, Chew et al

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