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In addition, prolonged activated partial-thromboplastin time (aPTT) has been observed in COVID-19 patients at higher rates than other patients, suggesting that COVID-19 may cause or exacerbate blood clotting abnormalities (21)

Some sources cite up to 60 days under optimal conditions, but 28 days is the conservative guideline most compounding pharmacies recommend

[1] When combined, the cumulative effect on heart rate and blood pressure may be clinically significant, particularly in patients with pre-existing cardiovascular disease, uncontrolled hypertension, or arrhythmias

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