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This rapid elevation of FFAs paralleled to a peak in plasma insulin, likely due to a direct effect of G49 in the pancreas via GLP-1R as OXM does 42

While these mechanisms support weight loss and metabolic improvements, they function differently from metabolic stimulants that directly increase energy expenditure or thermogenesis

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Act Nerv Super Rediviva 61:3138 Koziorowski D, Tomasiuk R, Szlufik S, Friedman A (2012) Inflammatory cytokines and NT-proCNP in Parkinsons disease patients