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Additionally, its anti-inflammatory properties suggest potential as a treatment for inflammatory bowel disease and other gastrointestinal issues, offering promising benefits for mucosal protection and overall digestive health (6)

PELE has widely been used to study ligand-protein interactions and protein dynamics at a fraction of the cost compared to other sampling methods such as molecular dynamics 58,59,60

Furthermore, SCFAs activate GPR43, leading to blocking IB phosphorylation and degradation, which inhibits NF-B activity and reduces inflammatory gene expression ( Figure 3 ) [88]

Differential gene expression and DNA methylation in the risk of depression in LOAD patients