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Whilst a direct causal link between retatrutide and joint pain has not been established, certain patient populations may be more predisposed to experiencing musculoskeletal symptoms during treatment whether related to the medication itself or to the physiological changes it induces

If skin symptoms persist despite these measures, your healthcare provider may consider adjusting your semaglutide dose, temporarily holding treatment to assess symptom resolution, or prescribing prescription-strength topical or oral medications

"We're seeing widespread use of these medications among women of childbearing age, but very little evidence that contraception is being considered as part of routine care," said paper author and pharmacist professor Luke Grzeskowiak in a statement

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