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Zepbound is indicated for chronic weight management in adult patients with obesity with a BMI (body mass index) of 30+, or who are overweight with a BMI of 27+ with weight-related medical health conditions

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On This Page Indications and Usage Dosage and Administration Dosage Forms and Strengths Contraindications Warnings and Precautions Adverse Reactions/Side Effects Drug Interactions Use In Specific Populations Overdosage Description Clinical Pharmacology Nonclinical Toxicology Clinical Studies How Supplied/Storage and Handling Patient Counseling Information Medication Guide Highlights of Prescribing Information RYBELSUS (semaglutide) tablets, for oral use OZEMPIC (semaglutide) tablets, for oral use Initial U.S

Concurrently, GLP-1RAs improve energy metabolism in astrocytes and neurons by elevating AMPK activity, thereby enhancing metabolic crosstalk between these cells