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Under physiological conditions, triiodothyronine (T3) maintains mitochondrial integrity by inducing PGC1-, Nrf1/Nrf2, and TFAM to stimulate mitochondrial biogenesis and fatty acid oxidation, while also activating AMPK signaling via integrin v3 (84, 85)

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Gastrointestinal Cytoprotection Originally studied in gastric lesion models, BPC-157 showed protective effects on: Gastric mucosa Intestinal healing Ulcer repair Reference: Sikiric et al., 1993 Gastric mucosal protection PubMed: Experimentally Observed Benefits of BPC 157 Peptides Below are benefits observed in controlled experimental models