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Melatonin supplementation alone, though, wasnt enough to return the AD mice to normal control levels, but the improvements were significant.[ref][ref][ref][ref] Another study using a mouse model of AD found that melatonin reduced the signs of Alzheimers, including cognitive deficits

Study 2 Before TBI, WT and Pgam5 -/- male mice drank water with ampicillin (1 g/L), vancomycin (500 mg/L), ciprofloxacin (200 mg/L), imipenem plus cilastatin (250 mg/L), and metronidazole (1 g/L) for 2 weeks, after which antibiotic treatment was discontinued and replaced with sterile tap water 72 h before the injury

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Brain Fog and Cognitive Impairment: Both NAC and glycine possess the ability to cross the blood-brain barrier to directly replenish cortical glutathione levels