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In rat experiments, a decrease in phylloquinone (vitamin K 1 ) and menaquinone-4 (a form of vitamin K 2 ) concentrations in extra-hepatic tissues was found in animals administered excess -tocopherol via the diet or by subcutaneous injection

10.1016/j.carbpol.2014.12.032 [DOI] [PubMed] [Google Scholar] Jiang T., Sun Q., Chen S

Evidence on melatonin's effects on insulin secretion and glucose tolerance is mixed and limited, whilst Wegovy improves glycaemic control in people with type 2 diabetes