noom glp-1 cost reddit Explain this to me : r/Noom Extremely disappointing Noom experience :

GLP-1 is an incretin hormone secreted from intestinal L-cells after food intake

In a notable study published in The Lancet , participants taking tesofensine over six months achieved an average weight loss of 10-12% of their initial body weight, with higher doses showing more pronounced effects

When pancreas compensates by secreting more insulin, fat accumulates (especially visceral fat), inflammation rises, and the body begins to defend this altered metabolic set-point as its new normal

Fever, vomiting, and reduced appetite deplete fluids and nutrients rapidly, and a compromised digestive system absorbs oral supplements poorly