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Contact your GP if you experience: No improvement after 46 weeks of treatment : Whilst neurological symptoms may take longer to resolve, you should notice some improvement in energy levels or general wellbeing within this timeframe

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Only a three monthly dose is needed . It is therefore more convenient for the patient and cheaper by dosage regimen and in the time required of nursing staff to administer injections So now, just two years later we have moved to 3 monthly injections WHY