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Mitochondrial membrane potential was evaluated through JC-1 assay on methamphetamine-treated SH-SY5Y cells, where pretreatment with lactoferrin- CAY10603-PLGA showed restoration of mitochondrial membrane potential, demonstrating effective reversal of mitochondrial dysfunction

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This balanced approach allows controlled removal of damaged ECM components while protecting newly synthesized proteins, with research showing BPC-157-treated wounds exhibit 60% increased collagen deposition combined with improved fiber organization compared to untreated controls