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However, the exact relationship between polyphenols and STAT3, as well as the specific mechanisms of inhibition, are areas of active research

In murine models, PCS treatment reduced pro-inflammatory factors (IL-1, IL-6, CCL3, and TNF-) and significantly increased the anti-inflammatory factor IL-10, thereby further alleviating hepatic inflammation

A Herxheimer reaction, also called a Herx or Jarisch-Herxheimer reaction, is a temporary physical response that can happen when the body is detoxifying or killing off harmful bacteria too quickly