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But, what are compounded GLP-1s, anyway

This distinction matters because 503B facilities face stricter FDA oversight, including current Good Manufacturing Practice (cGMP) requirements, than standard 503A pharmacies

If you were on a higher dose (1mg or above), your provider may recommend: - Restarting at your current dose if the gap was exactly 2 weeks - Stepping down one dose level if the gap was 24 weeks - Restarting the full titration from 0.25mg if the gap was more than 4 weeks **Why dose adjustment matters**: Your GI system de-adapts to semaglutide during extended breaks

This includes heart disease, stroke, type 2 diabetes, some cancers, and even heart attacks