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Moving from Tirzepatide to Semaglutide If you are switching from tirzepatide to semaglutide, your healthcare provider will likely have you start at a lower dose of semaglutide, usually 0.25 mg or 0.5 mg weekly

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No formal meta-analysis was conducted, and data were synthesized narratively to highlight trends in efficacy, safety, and mechanistic differences among single, dual, and triple incretin-based therapies