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Methods Animal Male C57BL/6J mice (H2b) and male Wistar rats were obtained from Japan SLC (Shizuoka, Japan) and male db/db mice were from CLEA Japan (Tokyo, Japan)

Pearson correlations were also calculated between metabolite levels and dimensional scores of ASD and ADHD symptom severity (respectively Conners and ADOS for the ASD group only)

These are some clues that the patient is experiencing a toxic burden and may need additional help with detoxification

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