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Vitamin B12 plays a critical role in supporting red blood cell formation, neurological health, and DNA synthesisdeficiencies can lead to fatigue, mood changes, and cognitive decline

Several technical reasons may explain our distinctive findings, including differences in the microbiome sampling site, the limited n per group, singly housing mice, or the use of highly similar lean, Western, and high-fat diets which systematically exchanged fat content with carbohydrate content

The perceived energy boost reported by non-deficient individuals is likely attributable to placebo effect

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