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When MSNs-ss-SA (approximately 90 nm in size) are applied to rice leaves, they are rapidly absorbed through the stomata, resulting in efficient cellular entry and uniform tissue distribution

The combined electrophysiological analysis further shows an overall reduction in functional expression of NR2A subunits along with relative increases in both, contribution of NR2B to the synaptic and extrasynaptic NMDAR-mediated currents and the magnitude of extrasynaptic NMDAR-mediated currents in lesioned HMNs

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Healthcare providers must balance the potential benefits of higher doses against individual patient factors, comorbidities, and treatment priorities when determining the optimal timing for dose adjustment