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Although tirzepatide did not meet the criterion for superiority to dulaglutide with respect to the primary endpoint, a prespecified subgroup analysis suggested a possible lower incidence of death from any cause and of death from noncardiovascular causes in the tirzepatide group than in the dulaglutide group

There was overlap of the trial population with the reimbursement criteria requested by the sponsor for the resubmission patients with a BMI of 27 kg/m 2 or greater and established CVD (MI, stroke, and/or PAD)

That distinction matters after the July 2026 advisory committee votes

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