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NICE guidance recommends early referral (within 3 working days) for suspected persistent synovitis to enable prompt initiation of disease-modifying therapy where appropriate

GLP1 receptors exist in areas of the brain involved in reward and addictive behaviors, which may explain why many patients naturally drink less during treatment

This causes patients to become increasingly dysbiotic as their immune system weakens over time, and successive infections may explain the variability of symptoms experienced in ME/CFS (193)