can you take metformin and tirzepatide

can you take metformin and tirzepatide I stop (Metformin) replace it with ( Tirzepatide) for weight loss in a patient with Chronic Kidney Disease (CKD) stage 3a and a well-controlled Hemoglobin A1c (HbA1c)? Is it safe to take

Name: can you take metformin and tirzepatide I stop (Metformin) replace it with ( Tirzepatide) for weight loss in a patient with Chronic Kidney Disease (CKD) stage 3a and a well-controlled Hemoglobin A1c (HbA1c)? Is it safe to take
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This imbalance leads to the infiltration of M1 macrophages, forming CD11c+ crown-like structures (CLS) around dead cells in WAT, resulting in the accumulation of high amounts of lipids within macrophages and promoting inflammation [99, 101]