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According Greenberg, it estimated that the total cost of MDD which includes productivity loss, suicide-related costs, and direct care cost, was $210.5 billion in 2010

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Furthermore, the mediation analysis should be interpreted with caution, as it assumes no confounding factors beyond those included in the model (baseline body weight and stratification factors), which may not be the case, given that postrandomization events (GI AEs) are used in the analysis