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Cerebrolysin has specific evidence in a diabetic neuropathy mouse model showing dose-dependent nerve fiber improvements

Mechanism of action of GLP-1 receptor agonists: Direct receptor binding These medications bind specifically to GLP-1 receptors on pancreatic beta cells, stimulating insulin secretion in a glucose-dependent manner (meaning they work when blood glucose is elevated)

Obesity, insulin resistance (IR), steroid hormones imbalance and intestinal microecological imbalance, deficiencies in vitamin D and selenium, as well as hyperhomocysteinemia (HHcy) can induce systematic imbalance between pro-inflammatory and anti-inflammatory cells and molecules

Topical and systemic GLP-1R agonist administration both rescue retinal ganglion cells in hypertensive glaucoma