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To achieve this objective, critical research priorities in subsequent clinical trials include: standardization of ESCM extracts, determination of safe dosage ranges, the differences in bioavailability of each constituent and their corresponding combination methods, as well as the development of personalized therapeutic regimens stratified by cancer subtypes

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Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2 (MEN2)