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In this rather important subgroup analysis based on high-quality RCT data from STRIDE, we showed that the benefit on objective walking capacity from treatment with semaglutide in persons with earlier stage PAD and concurrent T2DM was consistent across age groups and across a range of clinical markers of PAD severity, including in persons that had previously undergone a lower limb revascularisation procedure

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They also had a placebo group receiving dummy injections for comparison

A SAFETY NOTE: Retatrutide is injected once weekly (more precisely, Retatrutide should be injected on the same day each week)