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As fat stores deplete, the body undergoes stress that affects muscles, joints, and connective tissues beyond any single location

One of the theories that tries to explain the exercise effects defends that it may be in part due to the accumulation of oxidative damage induced by reactive oxygen species (ROS) and reactive nitrogen species (RNS) to cells and macromolecules [13]

These findings have led some researchers to explore whether addressing the autoimmune process more directly could improve patient outcomes

They produce lactic acid and serve as a defense against potential pathogens, but the effect was not significant ( Gardnerella vaginalis is less prevalent in individuals with optimal vaginal health