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Cancer treatments significantly elevate OS through multiple mechanisms: chemotherapeutic agents, particularly alkylating agents and platinum compounds, generate excessive ROS directly damaging sperm DNA and membranes (87, 88), while radiation therapy induces both acute and chronic OS states in testicular tissue, leading to prolonged spermatogenic dysfunction (95)
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47,48 GSH metabolism includes degradation and recycling
The 2020 Weston Lecture presented by Glaucoma Research Foundation featured world-renowned genetics researcher and best-selling author David Sinclair, PhD, AO discussing longevity research and glaucoma
It is also a tripeptide and is the primary regulator of cellular redox states
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