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Myslivecek, J

Preclinical investigations have showcased the plants capacity to modulate mitochondrial function and apoptosis, as well as mitigate inflammation through the inhibition of inflammatory markers such as cytokines (including IL-6 and TNF-), nitric oxide, and reactive oxygen species

It plays a vital role in detoxifying cells, neutralizing harmful free radicals, and supporting the immune system

Furthermore, anticholinergic medications, such as trihexyphenidyl, are used also in PD management but struggle to effectively cross the BBB and often exhibit non-specific binding, leading to undesirable peripheral effects such as dry mouth and cognitive impairment, particularly in elderly patients