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Precise control of operational parameterssuch as power, temperature, and extraction durationis essential, as excessive energy input or prolonged treatment can degrade sensitive polyphenolic structures, potentially lowering yield or altering compound profiles ( 3.1.4 Supercritical fluid extraction method Supercritical fluid extraction is an alternative two-step technique

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The virulence factor urease and its unexplored role in the metabolism of Cryptococcus neoformans