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Once retatrutide is tolerated at the 2 mg/week step typically 812 weeks in community references describe introducing cagrilintide at 0.25 mg/week and following a separate 4-week titration to maintenance

Furthermore, investigating patient-specific factors, including genetic predispositions and disease progression variability, will be critical for understanding the full therapeutic potential of GLP-1RAs and optimizing personalized treatment strategies for diabetes-related cognitive dysfunction

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