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Peptides are involved in many different processes in your body, so potential side effects depend on the peptide you are taking and how you're taking it

We therefore sought to investigate the molecular mechanisms by which GLP-1, oxyntomodulin, exendin-4 and exendin-P5 bind and activate the GLP-1R using a combination of structural biology, molecular dynamics simulations and pharmacological studies combined with extensive receptor mutagenesis

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The findings carry real-world implications particularly for the millions of older adults on weight-loss medications who may already be at risk for bone loss