The findings of the study indicated that although the liposomal hydroquinone 4% was efficient in melasma management and could induce a significant reduction in MASI score, however, no superiority was obvious in comparison to the conventional hydroquinone cream (Taghavi et al., 2019a)
10% w/v, pH 7.4) using Omni-125 hand-held homogenizer (Omni International, USA), then the homogenates were centrifuged using a cooling centrifuge at (2000 g , 15 min, 4 C), and the supernatant was divided into aliquots, where one aliquot was freshly used for assay of oxidative biomarkers, and the other one stored at 80 C to be used for enzyme-linked immunosorbent assay (ELISA)
It belongs to the Animalia kingdom and is in the Ranidae family
(4) Tocopheryl Acetate (Germany, 96% purity)