IGF-1 plays a major role in muscle growth, cellular repair, and tissue regeneration by stimulating protein synthesis and cellular proliferation
10.1021/bi9902182 13 FinkelT
J Pharm Pharmacol 68(8):10641072 Frattaruolo L, Carullo G, Brindisi M, Mazzotta S, Bellissimo L, Rago V, Curcio R, Dolce V, Aiello F, Cappello AR (2019) Antioxidant and anti-inflammatory activities of flavanones from Glycyrrhiza glabra L.(licorice) leaf phytocomplexes: identification of licoflavanone as a modulator of NF-kB/MAPK pathway
controls Rabbit wounds: GHK alone or combined with helium-neon laser improved wound contraction, boosted granulation tissue, increased antioxidant enzyme activity, and stimulated new blood vessel growth Diabetic rat models: PIC dressings with GHK showed higher glutathione and ascorbic acid levels, better epithelialization, and stronger fibroblast activation New Blood Vessel Formation Wounds cant heal without blood supply