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I always clarify to my patients the possibility that they will need to continue the medication long-term, Mora says

These effects typically become noticeable within 24-48 hours of the last injection and may persist for several days

The GLP-1 agonist, exenatide, increased fasting EF via endothelial nitric oxide (NO) synthase (eNOS) activation, nitric oxide (NO) production in endothelial cells, induced dose-dependent vasorelaxation, and reduced high-glucose or lipid-induced endothelial dysfunction in arterioles ex vivo [64]

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