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36 / IgA1 synthetic Hinge Region peptide fragment from Val222 to Cys241 with glycosylation (α-GalNAc) at Thr228
/ β-LacNAc-PEG3-Thiol / β-LacNAc-PEG3-SH
1 / Epilepsy And Bipolar Disorder (Mood Disorder) / Lamotrigine-13C d3 / 6-(2
Tri-GalNAc-PEG5-COOH
PE131000: α-GalNAc-PEG3-Alkyne label-new 36 / IgA1 synthetic HingeC17H29NO9 391. 41 An D N acetylgalactosamine (GalNAc) ligand equipped with a terminal alkyne through a hydrophilic PEG3 spacer. The alkyne couples to azide functionalized partners via copper catalyzed azide alkyne cycloaddition (CuAAC), forming stable 1,2,3 triazole linkages. This compound enables the construction of hepatocyte targeted therapeutics and research tools that exploit the asialoglycoprotein receptor (ASGPR), which is highly expressed on
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